When the Denver Broncos and Cincinnati Bengals square off under the primetime lights of Monday Night Football, much of the spotlight will fall on one crucial matchup: Bengals defensive end Trey Hendrickson against rookie Broncos quarterback Bo Nix. This battle in the trenches could determine not only the game’s outcome but also the direction of both teams’ seasons.

Hendrickson: The Bengals’ Defensive Anchor
Trey Hendrickson has been the heart of Cincinnati’s pass rush since arriving from New Orleans in 2021. Known for his relentless motor, quick first step, and ability to disrupt opposing quarterbacks, Hendrickson has consistently ranked among the league’s top edge rushers. This season, he’s once again proving to be a nightmare for offensive tackles, already racking up multiple sacks and countless pressures through the opening weeks.
For the Bengals, Hendrickson represents their best chance to derail the Broncos’ offensive rhythm. If he can consistently collapse the pocket and force Nix into rushed throws, the Bengals’ secondary will have opportunities to capitalize.
Bo Nix: A Rookie Under the Bright Lights
On the other side stands Bo Nix, Denver’s promising rookie quarterback. After a standout college career at Oregon, Nix has brought poise, accuracy, and mobility to a Broncos offense that’s been searching for stability. While rookies often struggle in primetime, Nix has shown maturity beyond his years, making smart reads and displaying confidence under pressure.
But Monday night presents his toughest test yet. Facing a ferocious pass rusher like Hendrickson is no small task, and how Nix handles the heat will reveal much about his readiness to lead Denver on a playoff push.

The Broncos’ Game Plan
Protecting Nix will be Denver’s top priority. Expect the Broncos to lean heavily on their offensive line, particularly left tackle Garett Bolles, to neutralize Hendrickson’s explosiveness off the edge. Additionally, the coaching staff may employ quick passing schemes, designed rollouts, and a strong running game to keep Hendrickson from pinning his ears back and charging straight at the rookie.
If the Broncos can establish balance early, Nix will have the time and confidence to find receivers downfield and challenge a Bengals defense that has been inconsistent in coverage.
The Bengals’ Defensive Blueprint
For Cincinnati, everything starts with pressure. Defensive coordinator Lou Anarumo will likely look to isolate Hendrickson in one-on-one matchups, forcing Denver to dedicate extra blockers his way. This could open up opportunities for blitzes from linebackers or interior linemen.
If Hendrickson can disrupt Nix early, forcing him into mistakes or sacks, it will tilt momentum firmly in Cincinnati’s favor. Conversely, if Nix neutralizes the pressure, the Bengals may find themselves struggling to keep up with Denver’s offensive tempo.
A Battle That Defines the Game
Every NFL matchup has its X-factor, and on Monday night, it’s Hendrickson vs. Nix. For the Bengals, Hendrickson’s dominance could be the difference between victory and disappointment. For the Broncos, Nix’s composure under fire may cement his reputation as a rising star.
In a game filled with playoff implications, this individual showdown will serve as the heartbeat of the contest. Fans can expect fireworks, drama, and a test of willpower between a seasoned pass rusher and a fearless rookie quarterback.