How to Watch Carolina Panthers vs. San Francisco 49ers: Week 12 Monday Night Football – Kickoff Time, TV Channel, Streaming Options, and More

Santa Clara, CA – November 21, 2025 – Monday Night Football returns in Week 12 with an intriguing NFC matchup as the Carolina Panthers (6-5) head west to face the San Francisco 49ers (7-4) at Levi’s Stadium. The surprising Panthers, riding a strong season under Bryce Young and Dave Canales, look to play spoiler against a 49ers team still chasing the NFC West crown despite injury challenges.

This is the first meeting between the two teams since 2022, and only Carolina’s second-ever Monday night appearance at Levi’s Stadium. With both teams in the playoff hunt, expect a physical, high-energy prime-time battle.

Kickoff Time Across U.S. Time Zones

The game is scheduled for Monday, November 24, 2025, with kickoff at:

• Eastern Time (ET): 8:15 PM
• Central Time (CT): 7:15 PM
• Mountain Time (MT): 6:15 PM
• Pacific Time (PT): 5:15 PM (local time in Santa Clara)
• Alaska Time (AKT): 4:15 PM
• Hawaii-Aleutian Time (HT): 3:15 PM

Gates at Levi’s Stadium open at 3:15 PM PT – get there early for the full Faithful experience!

TV Broadcast Information

• National TV: ESPN (also available on ESPN2 with ManningCast featuring Peyton and Eli Manning)
• Broadcast Team: Joe Buck (play-by-play), Troy Aikman (color analyst), Lisa Salters (sideline reporter)
• Spanish Language: ESPN Deportes

Pre-game coverage starts at 6:00 PM ET on ESPN with Monday Night Countdown.

Streaming Options

Monday Night Football is easier than ever to stream:

• ESPN+ or the ESPN App (authenticated with TV provider)
• Fubo (includes ESPN; free trial available)
• YouTube TV, Hulu + Live TV, Sling TV (Orange + Blue), DirecTV Stream – All carry ESPN
• NFL+ – Stream on mobile devices (primetime games included nationwide); full replay available after the game
• Disney+ / Hulu bundle – If you have the bundle, MNF streams directly

International viewers can watch on NFL Game Pass (DAZN in most countries) with no blackouts.

Radio and Audio Options

• 49ers fans: 49ers Radio Network – KNBR 680 AM / KSAN 107.7 FM (Greg Papa, Tim Ryan, and John Lund) 49ers feed on SiriusXM Channel 225 or the SiriusXM app
• Panthers fans: Panthers Radio Network (WBT 1110 AM / 99.3 FM) with Anish Shroff, Jake Delhomme, and Kristen Balboni. Panthers feed on SiriusXM Channel 381
• National radio: Westwood One with Ryan Radtke and Mike Golic

Weather Forecast for Levi’s Stadium

Typical late-November Bay Area evening: partly cloudy with temperatures around 58–62°F at kickoff, dropping to the low 50s by the fourth quarter. Light winds (5–10 mph) – perfect football weather with no rain expected.

The 49ers are currently favored by 7 points with the over/under at 48.5. San Francisco’s offense (led by Christian McCaffrey and Brock Purdy) faces a Carolina defense that’s been surprisingly stout, while Bryce Young looks to exploit a banged-up 49ers secondary.

Will the Faithful light up Levi’s on Monday night, or can Carolina pull off the upset? Don’t miss it – this one has serious playoff implications!

Tickets still available on Ticketmaster, 49ers.com, or Panthers.com. #FTF #KeepPounding